http://desimix.forumotion.com/health-f31/-t1.htm Sat, 05 Sep 2009 07:34:51 GMT 10 http://illiweb.com/fa/empty.gif http://desimix.forumotion.com/health-f31/-t1.htm http://desimix.forumotion.com/health-f31/risk-score-for-type-2-diabetes-t336.htm Emperor Risk score for type 2 diabetes Prediction of type 2 diabetes might enable lifestyle measures or prophylactic drug therapy to prevent or delay the onset of the disease. Now a UK cohort study has provided data for the development and validation of a computer-based score (the QDS score) to estimate the 10-year risk of type 2 diabetes. The derivation cohort included 2,540,753 people on the QResearch database with 16,436,135 person-years of data. Type 2 diabetes developed in 78,081 ... Health Tue, 01 Sep 2009 07:37:04 GMT http://desimix.forumotion.com/health-f31/risk-score-for-type-2-diabetes-t336.htm#435 http://desimix.forumotion.com/health-f31/risk-score-for-type-2-diabetes-t336.htm http://desimix.forumotion.com/health-f31/diabetics-can-protect-their-feet-t375.htm Emperor How People With Diabetes Can Protect Their Feet Being alert to signs of an infection can prevent far worse People living with diabetes often suffer nerve damage that numbs their extremities—a dangerous condition that can lead to sores and infection. Here's how to avoid a serious problem: Do a regular visual check: Check feet nightly before bed, advises Stephen Kominsky, a podiatric surgeon and diabetic foot expert at Washington Hospital Center in D.C. Daily exams ... Health Sat, 05 Sep 2009 07:34:51 GMT http://desimix.forumotion.com/health-f31/diabetics-can-protect-their-feet-t375.htm#475 http://desimix.forumotion.com/health-f31/diabetics-can-protect-their-feet-t375.htm http://desimix.forumotion.com/health-f31/esomeprazole-for-poorly-controlled-asthma-no-benefit-t346.htm Emperor Esomeprazole for poorly controlled asthma: No benefit It has been estimated that some 32–84% of people with asthma have gastro­oesophageal reflux, and in about half of those with reflux, it is asymptomatic. Researchers in the United States postulated that asymptomatic reflux might contribute to poorly controlled asthma and that use of a proton pump inhibitor might improve control of the asthma. They have found that it does not. A total of 412 people with poorly controlled ... Health Tue, 01 Sep 2009 07:43:18 GMT http://desimix.forumotion.com/health-f31/esomeprazole-for-poorly-controlled-asthma-no-benefit-t346.htm#445 http://desimix.forumotion.com/health-f31/esomeprazole-for-poorly-controlled-asthma-no-benefit-t346.htm http://desimix.forumotion.com/health-f31/imatinib-mesylate-for-gastrointestinal-stromal-tumour-t345.htm Emperor Imatinib mesylate for gastrointestinal stromal tumour In the United States, there are about 3,000–4,000 new cases of gastrointestinal stromal tumour (GIST) each year, usually arising in the stomach or small intestine. Most tumours (85%) have an activating mutation in the KIT proto-oncogene, and a minority (3–5%) have a mutation in the gene-encoding platelet-derived growth factor receptor-alpha (PDGFR-alpha). Imitinib mesylate selectively inhibits several tyrosine kinases, ... Health Tue, 01 Sep 2009 07:42:55 GMT http://desimix.forumotion.com/health-f31/imatinib-mesylate-for-gastrointestinal-stromal-tumour-t345.htm#444 http://desimix.forumotion.com/health-f31/imatinib-mesylate-for-gastrointestinal-stromal-tumour-t345.htm http://desimix.forumotion.com/health-f31/hot-tea-and-oesophageal-cancer-t344.htm Emperor Hot tea and oesophageal cancer A very high rate of oesophageal cancer in Golestan province, northern Iran, has led to a search for causes. Smoking and alcohol are not implicated, and there is no sex difference. Factors that might be important include poor intake of fruit and vegetables, low socio-economic status and drinking very hot tea. The association with hot tea has been corroborated in a population-based case-control study. The case-control study included 300 cases of histologically ... Health Tue, 01 Sep 2009 07:42:24 GMT http://desimix.forumotion.com/health-f31/hot-tea-and-oesophageal-cancer-t344.htm#443 http://desimix.forumotion.com/health-f31/hot-tea-and-oesophageal-cancer-t344.htm http://desimix.forumotion.com/health-f31/moxifloxacin-vs-ethambutol-for-tuberculosis-t343.htm Emperor Moxifloxacin vs ethambutol for tuberculosis New anti-tuberculous drugs are needed because of the spread of drug resistance and because drugs that allow the length of the treatment course to be shortened would improve compliance and, therefore, cure rates. The fluoroquinalone moxifloxacin is bactericidal against Mycobacterium tuber­culosis. Now a phase II study in Brazil has given promising results. At a hospital in Rio de Janeiro, 170 adult patients with sputum smear-positive ... Health Tue, 01 Sep 2009 07:41:50 GMT http://desimix.forumotion.com/health-f31/moxifloxacin-vs-ethambutol-for-tuberculosis-t343.htm#442 http://desimix.forumotion.com/health-f31/moxifloxacin-vs-ethambutol-for-tuberculosis-t343.htm http://desimix.forumotion.com/health-f31/parenteral-drug-errors-on-icu-t342.htm Emperor Parenteral drug errors on ICU The first multinational sentinel events evaluation (SEE1) study, reported in 2006, showed an incidence of drug errors of almost 40 incidents per 100 patient-days in intensive care units (ICUs). Now the results of a second study (SEE2) have been reported. The observational prospective, 24-hour, cross-sectional study included 1,328 adult patients in 113 ICUs in 27 countries. A total of 861 errors in the administration of parenteral drugs affected ... Health Tue, 01 Sep 2009 07:40:17 GMT http://desimix.forumotion.com/health-f31/parenteral-drug-errors-on-icu-t342.htm#441 http://desimix.forumotion.com/health-f31/parenteral-drug-errors-on-icu-t342.htm http://desimix.forumotion.com/health-f31/brown-fat-in-adults-t341.htm Emperor Brown fat in adults Adipose tissue is of two kinds, white and brown. Accumulation of white fat constitutes obesity, whereas brown fat contributes to thermogenesis and might restrict the development of obesity. Brown fat is plentiful in small mammals and human newborn infants, but has been thought to be unimportant in human adults. Now evidence has accumulated that brown fat is, in fact, present in significant amounts in human adults and may be physiologi­cally important. It ... Health Tue, 01 Sep 2009 07:39:26 GMT http://desimix.forumotion.com/health-f31/brown-fat-in-adults-t341.htm#440 http://desimix.forumotion.com/health-f31/brown-fat-in-adults-t341.htm http://desimix.forumotion.com/health-f31/avotermin-to-improve-skin-scarring-t340.htm Emperor Avotermin to improve skin scarring A factor produced by skin keratinocytes and fibroblasts may prevent unsightly scarring. Animal experiments have shown that injection of transforming growth factor­beta-3 (TGF-beta-3) into the skin of surgical wounds improved the subsequent scar. Now three studies in Manchester, England, have confirmed better wound healing after application of avotermin (recombinant, active, human TGF-beta-3). The three studies included 223 healthy men and ... Health Tue, 01 Sep 2009 07:38:57 GMT http://desimix.forumotion.com/health-f31/avotermin-to-improve-skin-scarring-t340.htm#439 http://desimix.forumotion.com/health-f31/avotermin-to-improve-skin-scarring-t340.htm http://desimix.forumotion.com/health-f31/nicotine-replacement-therapy-a-systematic-review-t339.htm Emperor Nicotine-replacement therapy: A systematic review A systematic review and meta-analysis has addressed the issue of whether nicotine-replacement therapy is worthwhile when given to reduce and eventually stop smoking in people who have no intention of quitting in the short term. Seven placebo-controlled trials were included. They were trials of reduction of smoking and included a total of 2,767 people given nicotine-replacement therapy for 6–18 months. Sustained abstinence ... Health Tue, 01 Sep 2009 07:38:32 GMT http://desimix.forumotion.com/health-f31/nicotine-replacement-therapy-a-systematic-review-t339.htm#438 http://desimix.forumotion.com/health-f31/nicotine-replacement-therapy-a-systematic-review-t339.htm http://desimix.forumotion.com/health-f31/reduced-risk-of-ulcerative-colitis-after-appendicitis-or-mesenteric-lymphadenitis-in-childhood-t338.htm Emperor Reduced risk of ulcerative colitis after appendicitis or mesenteric lymphadenitis in childhood There is evidence from case-control and cohort studies that people who have had an appendicectomy are less likely to develop ulcerative colitis, but it is not known if the effect is due to the operation or its underlying cause. Now combined nationwide cohort studies in Sweden and Denmark have linked the protective effect to appendicitis or mesenteric lymphadenitis, and not to the operation. A ... Health Tue, 01 Sep 2009 07:38:09 GMT http://desimix.forumotion.com/health-f31/reduced-risk-of-ulcerative-colitis-after-appendicitis-or-mesenteric-lymphadenitis-in-childhood-t338.htm#437 http://desimix.forumotion.com/health-f31/reduced-risk-of-ulcerative-colitis-after-appendicitis-or-mesenteric-lymphadenitis-in-childhood-t338.htm http://desimix.forumotion.com/health-f31/calcium-dobesilate-does-not-prevent-diabetic-macular-oedema-t337.htm Emperor Calcium dobesilate does not prevent diabetic macular oedema In patients with diabetic retinopathy, visual loss may result from blood vessel leakage and poor retinal perfusion. Calcium dobesilate might reduce vascular permea­bility and promote endothelium-dependent vasodilation and, therefore, prevent macular oedema. Now a multinational study has shown that calcium dobesilate does not prevent clinically significant macular oedema (CSME). A total of 635 patients with adult-onset ... Health Tue, 01 Sep 2009 07:37:30 GMT http://desimix.forumotion.com/health-f31/calcium-dobesilate-does-not-prevent-diabetic-macular-oedema-t337.htm#436 http://desimix.forumotion.com/health-f31/calcium-dobesilate-does-not-prevent-diabetic-macular-oedema-t337.htm http://desimix.forumotion.com/health-f31/polypill-and-cardiovascular-risk-factors-t335.htm Emperor Polypill and cardiovascular risk factors It has been calculated that a polypill of risk-reducing drugs could lower the risk of cardiovascular events in apparently healthy people by more than 80%. Now a trial in India has confirmed that use of such a pill reduces risk factors. A total of 2,053 people aged 45–80 years and without cardiovascular disease, but with one risk factor, were randomized at 50 centres to a polypill (Polycap) containing thiazide, 12.5 mg; atenolol, ... Health Tue, 01 Sep 2009 07:36:38 GMT http://desimix.forumotion.com/health-f31/polypill-and-cardiovascular-risk-factors-t335.htm#434 http://desimix.forumotion.com/health-f31/polypill-and-cardiovascular-risk-factors-t335.htm http://desimix.forumotion.com/health-f31/non-invasive-prenatal-diagnosis-from-dream-to-reality-t334.htm Emperor Non-invasive Prenatal Diagnosis: From Dream to Reality Non-invasive prenatal diagnosis (NIPD) is a long-sought goal. Research in the last decade on cell free fetal deoxyribonucleic acid (cffDNA), however, has revolutionized our understanding of NIPD. More recently, the presence of fetal ribonucleic acid (RNA) in maternal plasma was also discovered. These breakthroughs have opened up new possibilities for NIPD, as well as non-invasive prenatal study and monitoring of fetal physiology ... Health Tue, 01 Sep 2009 07:35:51 GMT http://desimix.forumotion.com/health-f31/non-invasive-prenatal-diagnosis-from-dream-to-reality-t334.htm#433 http://desimix.forumotion.com/health-f31/non-invasive-prenatal-diagnosis-from-dream-to-reality-t334.htm